According to The Rundown AI on X, Isomorphic Labs’ drug-design system more than doubled AlphaFold 3 performance on the hardest protein-ligand cases, signaling major gains in structure-based drug discovery; the post also notes Demis Hassabis previously won the Nobel Prize for AlphaFold and quoted his 2025 remark, “One day maybe we can cure all disease with the help of AI.” As reported by The Rundown AI, this leap suggests faster hit identification, improved binding predictions, and shorter lead optimization cycles for pharma pipelines. According to the cited post, the results highlight commercial opportunities in licensing AI-native discovery platforms, partnering with big pharma for target classes with sparse data, and deploying active learning loops to cut wet-lab iteration costs.